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genesis
Change of chromatin structure
Silencing of tumor suppressor gene(p53)
Reactivation of tumorigenesis genes(angiogenic factor)
Tumorigenesis
HDAC 결합인자
Mi-2β(chromatin remodeling factor)
MTA(metastasis-associated factors)
HAT,HDAC mechanism
HDAC isotypes
Class I - Rpd3 와 유사
H
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to the treatment of the acquired immune deficiency syndrome(AIDS). J. Med. Chem., 29, 1561-1569.
영문초록:
The Etiologic Agent For Acquired
Immunodeficiency Syndrome
Won-young Lee, Sc.D.
In 1981, an unusual case with immunodeficiency was reported and there after an epidemic of the similar syndrome i
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and HPA axis.
Future areas of research intrest include activation or modulation of leptin receptors and overcomming leptin resistance with high pharmacological doses of leptin or its congeners. All of these objectives are still somewhat elusive, and a lot of research needs to be weaved together to a
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and multicomplex nature.
Fifth, the socio-cultural meanings of kitsch appearing in fas-hion are as follows: the extension of commercialism which gra-tifies the pleasure-seeking mass consumers, the enlargement o-f the aesthetic category by inclining to everyday commonplace aesthetic sense, the expre
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세포 기전을 활성화 시키는 생화학적 신호로 전환되어 IL-1β 와 PGE2가 증가하고 이어서 OPG와 RANKL을 조절하여 결과적으로 골 흡수를 유도한다.(Fig.3)
< Fig.3 The response of PDL cells according to the type of mechanical strain. Tensile effect (A) and compressive effect (
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The role of RNA interference in heterochromatin silencing. Nature. (2004)431:364-370
Montgomery MK. RNA interference:historical overview and significance. Methods Mol Biol. (2004)265:3-21
Murchison EP, Hannon GJ. miRNAs on the move: miRNA biogenesis and the RNAi machinery. Curr Opin Cell Biol. (2004
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general concern of stroke including incidence, types, rehabilitation treatment, and concept of brain plasticity.
Incidence of stroke is on an increasing trend according to increasing geriatric population. The most common age of onset was 60s only 10 years ago but it become common at 30s to 40s aged
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세포 배양
5)Modes of culture
4. Three-dimensional culture techniques
1)Organ culture
2)Reconstruction of structure three-dimensional
3)조직 배양의 4가지 type
4)Application of IVF and embryo transfer
5.Genetic engineering of animal cells
1)Transient expression 한시적발현
2)Cloning expres
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and then sorting through the debris for the particular gene we want. For this to work a gene probe for the gene is needed, which means at least a short part of the gene’s sequence must be known.
12.Antisense Genes
These are used to turn off the expression of a gene in a cell. The principle is very
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genes are incorporated, no way to get them out
· AZT, and other drugs slow the course of the disease and increase life span(역전사방해)
· Researchers continue to develop drugs and to work toward an AIDS vaccine Cellular Defenders
Immune Responses
A. Innate Defenses of Humans
1. Physical Barr
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